Simplified Signal Decoding Systems in the Mechanistic Account of the Explanation of the Secondary Immune Response (in Polish)

Main Article Content

Tomasz Rzepiński

Abstract

The paper deals with the procedure of explaining the secondary immune response. First, the basic concepts of the mechanistic account of explanation developed by Machamer, Darden and Craver will be considered. Subsequently, I will focus on the concepts describing the activation of the elements of the immunological system viewed as a signal decoding process. The analysis will make it possible to argue for the thesis that the explanations of the secondary immune response, formulated in immunology, aim to describe the possible procedures of simplifying the signal decoding process. The following considerations will make it possible to show the specificity of the mechanistic explanations formulated in immunology, and to demonstrate their significance for medical sciences.

Downloads

Download data is not yet available.

Article Details

How to Cite
Rzepiński, Tomasz. 2016. “Simplified Signal Decoding Systems in the Mechanistic Account of the Explanation of the Secondary Immune Response (in Polish)”. Diametros, no. 50 (December):43-62. https://doi.org/10.13153/diam.50.2016.976.
Section
Articles
Author Biography

Tomasz Rzepiński, Adam Mickiewicz University

Tomasz Rzepiński, dr hab.Adam Mickiewicz UniversityDepartment of Philosophyul. Szamarzewskiego 89cPl-60-568 Poznań

E-mail: rzepinskit@wp.pl

Share |

References

Brzeziński [1995] – T. Brzeziński, Choroby, ich rozprzestrzenianie i historia, [w:] Historia medycyny, T. Brzeziński (red.), Wydawnictwo Lekarskie PZWL, Warszawa 1995, s. 114-122.
View in Google Scholar

Bushar, Farber [2008] – N. Bushar, D. Farber, Recalling the Year in Memory T Cells, „Annals of the New York Academy of Science” (1143) 2008, s. 212-225.
View in Google Scholar

Champagne, Dumont, Sekaly [2001] – P. Champagne, A. Dumont, R. Sekaly, Learning to remember: generation and maintance of T-cell memory, „DNA and Cell Biology” (20/12), 2001, s. 745-760.
View in Google Scholar

Craver [2007] – C. Craver, Explaining the Brain. Mechanisms and the Mosaic Unity of Neuroscience, , Oxford University Press, Oxford 2007.
View in Google Scholar

Crotty, Ahmed [2004] – S. Crotty, R. Ahmed, Immunological memory in humans, „Seminars in Immunology” (16) 2004, s. 197-203.
View in Google Scholar

Farber [2000] – D. Farber, T Cell Memory: Heterogenity and Mechanism, „Clinical Immunology” (95/3) 2000, s. 173-181.
View in Google Scholar

Farber [2003] – D. Farber, Remembrance of Antigens Past: New Insights into Memory T Cells, „Scandinavian Journal of Immunology” (58) 2003, s. 145-154.
View in Google Scholar

Garcia, DiSanto, Stockinger [1991] – S. Garcia, J. DiSanto, B. Stockinger, Following development of a CD4 T cell response in vivo: from activation to memory formation, „Immunity” (11) 1991, s. 163-71.
View in Google Scholar

Gourley, Wherry, Masopust, Ahmed [2004] – T. Gourley, E. Wherry, D. Masopust, R. Ahmed, Generation and maintance of immunological memory, „Seminars in Immunology” (16) 2004, s. 323-333.
View in Google Scholar

Gray [2001] – D. Gray, Immunological memory: a function of antigen persistence, „Trends in Microbiology” (1) 2001, s. 39-41.
View in Google Scholar

Gray, Matzinger [1991] – D. Gray, P. Matzinger, T cell memory is short-lived in the absence of antigen, „The Journal of Experimental Medicine” (174/5) 1991, s. 969-974.
View in Google Scholar

Grzesiowski, Hryniewicz [2005] – P. Grzesiowski, W. Hryniewicz, Immunologia szczepień ochronnych, [w:] Immunologia, J. Gołąb, M. Jakóbisiak, W. Lasek (red.), Wydawnictwo Naukowe PWN, Warszawa 2005, s. 356-371.
View in Google Scholar

Hempel [1965] – C. Hempel, Aspects of Scientific Explanation and other Essays in the Philosophy of Science, The Free Press, New York 1965.
View in Google Scholar

Jakóbisiak [2005] – M. Jakóbisiak, Główne komponenty i zasadnicze cechy odpowiedzi immunologicznej, [w:] Immunologia, J. Gołąb, M. Jakóbisiak, W. Lasek (red.), Wydawnictwo Naukowe PWN, Warszawa 2005, s. 1-6.
View in Google Scholar

Kaech, Wherry, Ahmed [2002] – S. Kaech, E. Wherry, R. Ahmed, Effector and memory T-cell differentiation: implications for vaccine development, Nature Reviews Immunology (2) 2002, s. 251-62.
View in Google Scholar

Kozar, Zagożdżon [2005] – K. Kozar, R. Zagożdżon, Aktywacja limfocytów, [w:] Immunologia, J. Gołąb, M. Jakóbisiak, W. Lasek (red.), Wydawnictwo Naukowe PWN, Warszawa 2005, s. 176-197.
View in Google Scholar

Machamer, Darden, Craver [2000] – P. Machamer, L. Darden L., C. Craver, Thinking about Mechanisms, Philosophy of Science, (67/1) 2000, s. 1-25.
View in Google Scholar

Maruyama, Lam, Rajewsky [2000] – M. Maruyama, K. Lam, K. Rajewsky, Memory B-cell persistence is independent of persisting immunizing antygen, “Nature”, (407) 2000, s. 636-42.
View in Google Scholar

McLaughlin [2001] – P. McLaughlin, What Function Explain – Functional Explanation and Self-Reproducing Systems, Cambridge University Press, Cambidge 2001.
View in Google Scholar

Nagel [1960] – E. Nagel, The Structure of Science – Problems in the Logic of Scientific Explanation, Routledge & Kegan Paul, London 1960.
View in Google Scholar

Nervi [2010] – M. Nervi, Mechanisms, Malfunction and Explanation in Medicine, “Biology & Philosophy”, 25(2), 2010, s. 215-228.
View in Google Scholar

Rzepiński [2013] – T. Rzepiński, Wyjaśnianie funkcjonalno-przyczynowe i jego rola w projektowaniu farmakologicznych terapii kardioprotekcyjnych, „Filozofia Nauki” (3/83) 2013, s. 99-121.
View in Google Scholar

Rzepiński [2014] – T. Rzepiński, Charakterystyka systemów dekodowania sygnału w mechanistycznej teorii wyjaśnień, „Filozofia Nauki” (3/87) 2014, s. 81-104.
View in Google Scholar

Saalmuller [2006] – A. Saalmuller, New understanding of immunological mechanisms, „Veterinary Microbiology” (117) 2006, s. 32-38.
View in Google Scholar

Salmon [1984] – W. Salmon, Scientific Explanation and the Causal Structure of the World, Princeton University Press, Princeton 1984.
View in Google Scholar

Thagard [2003] – P. Thagard, Pathways to Biomedical Discovery, „Philosophy of Science” 70(2) 2003, s. 235-254.
View in Google Scholar

Zinkernagel, Bachmann, Kundig, i współ. [1996] – R. Zinkernagel, M. Bachmann, T. Kundig, i współ. On immunological memory, „Annual Review of Immunology” (14) 1996, s. 333-67.
View in Google Scholar